She's best known for her roles on the sitcom Who's the Boss? and as Phoebe Halliwell on the fantasy series Charmed.
She began her career at the age of eight when she won a part in an open audition for a national tour of Annie. One of her first acting roles was at the age of 10 in the television program Who's the Boss?, alongside Tony Danza, Judith Light, Danny Pintauro, and Katherine Helmond.
In 1985, Alyssa played the role of Arnold Schwarzenegger's daughter in Commando.
At the beginning of her career Alyssa was known mainly for her role as Samantha Micelli on Who's the Boss? (1984-1992). She tried to shed her "nice girl" image by appearing in several films targeted at adults, such as Casualties of Love: The Long Island Lolita Story (1993), Embrace of the Vampire (1994), Confessions of a Sorority Girl (1994), Deadly Sins (1995), and Poison Ivy II: Lily (1996). She gained more mainstream success in TV as Jennifer Mancini on Melrose Place (1997-1998), Meg Winston in Spin City and most notably as Phoebe Halliwell on Charmed (1998-2006). Both Alyssa and Holly Marie Combs became producers for Charmed during the show's fifth season.

Public Name: Alyssa Jayne Milano
Birth Name: Alyssa Jayne Milano
Date of Birth: December 19, 1972
Place of Birth: Brooklyn, New York City

Filmography

1. Me and Everyone Else, 2007 (TV) (pre-production)
2. The Blue Hour, 2007 (post-production)
3. "Charmed", 1998-2006 TV Episodes
4. Dinotopia: Quest for the Ruby Sunstone, 2005 (voice)
5. Jimmy Neutron: You Bet Your Life Form, 2004 (TV) (voice)
6. "The Adventures of Jimmy Neutron: Boy Genius", 2004 TV Episode (voice)
7. Dickie Roberts: Former Child Star, 2003
8. Kiss the Bride, 2002
9. Buying the Cow, 2002
10. "Spin City", 1997-2001 TV Episodes
11. Lady and the Tramp II: Scamp's Adventure, 2001 (V) (voice)
12. "Diamond Hunters", 2001 (mini) TV Series
13. "Fantasy Island", 1998 TV Episode
14. "Melrose Place", 1997-1998 TV Episodes
15. Goldrush: A Real Life Alaskan Adventure, 1998 (TV)
16. Hugo Pool, 1997
17. Below Utopia, 1997
18. Public Enemies, 1996
19. To Brave Alaska, 1996 (TV)
20. Glory Daze, 1996
21. Fear, 1996
22. Poison Ivy II, 1996
23. Jimmy Zip, 1996
24. The Surrogate, 1995 (TV)
25. "The Outer Limits", 1995 TV Episode
26. Deadly Sins, 1995
27. Double Dragon, 1994
28. Confessions of a Sorority Girl, 1994 (TV)
29. Embrace of the Vampire, 1994
30. Candles in the Dark, 1993 (TV)
31. Casualties of Love: The Long Island Lolita Story, 1993 (TV)
32. The Webbers, 1993 (TV)
33. Conflict of Interest, 1993
34. Where the Day Takes You, 1992
35. "Who's the Boss?", 1984-1992 TV Episodes
36. Little Sister, 1992
37. The American Film Institute Presents: TV or Not TV?, 1990 (TV)
38. "Série rose", 1990 TV Episode
39. Speed Zone!, 1989
40. Dance 'Til Dawn, 1988 (TV)
41. Crash Course, 1988 (TV)
42. The Canterville Ghost, 1986 (TV)
43. Commando, 1985
44. Old Enough, 1984